During public comment, Nina Zeldes of Public Citizen's Health Research Group said the substance's supposed benefits are " largely based on anecdotal evidence" and that interest in it " appears to be driven by those who stand to benefit from increased demand
PMID: 11121126 Lamb JR, Crawford ED, Peck D, et al
Understanding how long semaglutide takes to work at each dose level helps set appropriate expectations for the slower schedule
While it does give relief, its effectiveness compared to more traditional treatments like metronidazole or azelaic acid is less proven, but more studies will help prove its effectiveness
Although in general its evolution is mild and self-limited, it can lead to neuroglycopaenia and compromise the patient's safety and quality of life
This is significant because leptin has its primary effects in the brain but does not cross the blood-brain barrier as readily as MT-2